Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Mutation detection by capillary denaturing high-performance liquid chromatography using monolithic columns.

Journal of biochemical and biophysical methods - 30 Jan 2001

Huber C G, Premstaller A, Xiao W, Oberacher H, Bonn G K, Oefner P J

Abstract excerpt

The high resolving power of the chromatographic separation of single- and double-stranded nucleic acids in 200 microm i.d. monolithic poly(styrene-divinylbenzene) capillary columns was utilized for mutation screening in polymerase chain reaction amplified polymorphic loci. Recognition of mutations is based on the separation of homo- and heteroduplex species by ion-pair reversed-phase high-performance liquid...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Chromatography, High Pressure Liquid
Share to DNA

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to DNA Mutational Analysis

Share to DNA Primers

Share to Heterozygote

Share to Homozygote

Share to Nucleic Acid Denaturation

Share to Polymerase Chain Reaction

Source

Identifiers

PMID: 11179757
DOI: 10.1016/s0165-022x(00)00147-0

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Mutation detection by capillary denaturing high-performance liquid chromatography using monolithic columns.PMID 11179757Read ↗

Denaturing HPLC for mutation screening.Semantic proximity Read ↗

Allelic discrimination by denaturing high-performance liquid chromatography.Semantic proximity Read ↗

Denaturing high-performance liquid chromatography for mutation detection and genotyping.Semantic proximity Read ↗

Denaturing high-performance liquid chromatography: A review.Semantic proximity Read ↗

Mutation and single nucleotide polymorphism detection using temperature gradient capillary electrophoresis.Semantic proximity Read ↗

A comparison of fluorescent SSCP and denaturing HPLC for high throughput mutation scanning.Semantic proximity Read ↗

Denaturing high-performance liquid chromatography for mutation detection and genotyping.Semantic proximity Read ↗

Capillary electrophoresis of gene mutation.Semantic proximity Read ↗

Sequencing using capillary electrophoresis of short tandem repeat alleles separated and purified by high performance liquid chromatography.Semantic proximity Read ↗

The use of denaturing high-performance liquid chromatography (DHPLC) for the analysis of genetic variations: impact for diagnostics and pharmacogenetics.Semantic proximity Read ↗

Integrated platform for detection of DNA sequence variants using capillary array electrophoresis.Semantic proximity Read ↗

High-throughput, high-sensitivity genetic mutation detection by tandem single-strand conformation polymorphism/heteroduplex analysis capillary array electrophoresis.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.