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Article

Tumor necrosis factor-alpha gene mutations and genotype changes in renal cell carcinoma.

The Journal of urology - 1 Feb 2001

Nakajima K, Sasaki M, Nojima D, Oh B R, Ishii N, Miura K, Dahiya R

Abstract excerpt

PURPOSE: We tested the hypothesis that genotype changes in the promoter region of tumor necrosis factor-alpha and exon 1 are associated with renal cell carcinoma. MATERIALS AND METHODS: We analyzed genotypic changes at the 3 polymorphic loci of tumor necrosis factor-alpha -238, -308 and 488 using tumor and normal tissues from 81 Japanese patients with renal cell carcinoma. RESULTS: Of the 81 patients 14 (17%) had...

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PMID: 11176446
DOI: 10.1097/00005392-200102000-00082

Genes

TNF

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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