Article
Association of bladder tumors and GA genotype of -308 nucleotide in tumor necrosis factor-alpha promoter with greater tumor necrosis factor-alpha expression.
Urology - 1 Nov 2004
Jeong Pildu, Kim Eun-Jung, Kim Eung-Gook, Byun Seok-Soo, Kim Choung Soo, Kim Wun-Jae
Abstract excerpt
OBJECTIVES: To investigate whether the genetic polymorphism of the -308 nucleotide in the tumor necrosis factor-alpha (TNF-alpha) promoter is associated with bladder cancer. METHODS: DNA samples from blood and tumor were analyzed by polymerase chain reaction-based restriction fragment length polymorphism to characterize the genetic polymorphism of the -308 nucleotide in the TNF-alpha promoter. TNF-alpha mRNA...
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