Article
Platelet-endothelial cell interactions in cerebral malaria: the end of a cordial understanding.
Thrombosis and haemostasis - 1 Dec 2009
Faille Dorothée, El-Assaad Fatima, Alessi Marie-Christine, Fusai Thierry, Combes Valéry, Grau Georges E
Abstract excerpt
Cerebral malaria is an acute encephalopathy evolving from an infection with Plasmodium falciparum which kills more than one million people each year. Brain tissues from patients who died with cerebral malaria revealed multifocal capillary obstruction by parasitised red blood cells, platelets, and leukocytes. Many studies are unified in their proposal of two major hypotheses consisting of cell adhesion to the...
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