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Article

Functional alteration of red blood cells by a megadalton protein of Plasmodium falciparum.

Blood - 22 Jan 2009

Glenister Fiona K, Fernandez Kate M, Kats Lev M, Hanssen Eric, Mohandas Narla, Coppel Ross L, Cooke Brian M

Abstract excerpt

Proteins exported from Plasmodium falciparum parasites into red blood cells (RBCs) interact with the membrane skeleton and contribute to the pathogenesis of malaria. Specifically, exported proteins increase RBC membrane rigidity, decrease deformability, and increase adhesiveness, culminating in intravascular sequestration of infected RBCs (iRBCs). Pf332 is the largest (>1 MDa) known malaria protein exported to...

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Identifiers

PMID: 18832660
DOI: 10.1182/blood-2008-05-157735
PMCID: PMC2630277

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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