Article
Drosophila homologues of the transcriptional coactivation complex subunits TRAP240 and TRAP230 are required for identical processes in eye-antennal disc development.
Development (Cambridge, England) - 1 Feb 2001
Treisman J
Abstract excerpt
We have identified mutations in two genes, blind spot and kohtalo, that encode Drosophila homologues of human TRAP240 and TRAP230, components of a large transcriptional coactivation complex homologous to the yeast Mediator complex. Loss of either blind spot or kohtalo has identical effects on the...
Topics
- Amino Acid Sequence
- Animals
- Cell Differentiation
- Cell Division
- Cloning, Molecular
- Drosophila
- Drosophila Proteins
- Extremities
- Eye Proteins
- Hedgehog Proteins
- Immunohistochemistry
- In Situ Hybridization
- Insect Proteins
- Mediator Complex
- Membrane Proteins
- Molecular Sequence Data
- Morphogenesis
- Mutation