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Non-mevalonate isoprenoid biosynthesis: enzymes, genes and inhibitors

1 Dec 2000

Abstract excerpt

The essential steps of the novel non-mevalonate pathway of isopentenyl diphosphate and isoprenoid biosynthesis in plants are described. The first five enzymes and genes of this 1-deoxy-D-xylulose 5-phosphate/2-C-methyl-D-erythritol 4-phosphate (DOXP/MEP) pathway are known. The herbicide fosmidomycin specifically blocks the second enzyme, the DOXP reductoisomerase. The DOXP/MEP pathway is also present in several...

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PMID: 11171208
DOI: 10.1042/bst0280785

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