Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Metabolic plasticity for isoprenoid biosynthesis in bacteria

25 Apr 2013

Abstract excerpt

Isoprenoids are a large family of compounds synthesized by all free-living organisms. In most bacteria, the common precursors of all isoprenoids are produced by the MEP (methylerythritol 4-phosphate) pathway. The MEP pathway is absent from archaea, fungi and animals (including humans), which synthesize their isoprenoid precursors using the completely unrelated MVA (mevalonate) pathway. Because the MEP pathway is...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Microbial Natural Products and Biosynthesis
Share to Photosynthetic Processes and Mechanisms
Share to Plant biochemistry and biosynthesis

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 23614721
DOI: 10.1042/bj20121899

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Metabolic plasticity for isoprenoid biosynthesis in bacteriaPMID 23614721Read ↗

Isoprenoid biosynthesis in bacterial pathogensSemantic proximity Read ↗

The MEP Pathway: A New Target for the Development of Herbicides, Antibiotics and Antimalarial DrugsSemantic proximity Read ↗

Investigating Novel IspE Inhibitor of MEP Pathway in MycobacteriumSemantic proximity Read ↗

Development of Inhibitors of the 2<i>C</i>-Methyl-<scp>d</scp>-erythritol 4-Phosphate (MEP) Pathway Enzymes as Potential Anti-Infective AgentsSemantic proximity Read ↗

The plastidial MEP pathway: unified nomenclature and resources.Semantic proximity Read ↗

The Multifaceted MEP Pathway: Towards New Therapeutic PerspectivesSemantic proximity Read ↗

Escherichia coli engineered to synthesize isopentenyl diphosphate and dimethylallyl diphosphate from mevalonate: a novel system for the genetic analysis of the 2-C-methyl-d-erythritol 4-phosphate pathway for isoprenoid biosynthesis.Semantic proximity Read ↗

Mutations in Escherichia coli aceE and ribB genes allow survival of strains defective in the first step of the isoprenoid biosynthesis pathway.Semantic proximity Read ↗

Biosynthesis of plant isoprenoids: perspectives for microbial engineering.Semantic proximity Read ↗

Identification of lethal mutations in Escherichia coli genes encoding enzymes of the methylerythritol phosphate pathway.Semantic proximity Read ↗

Reconstituted ferredoxin-MEP pathway of Apicomplexa in Escherichiacoli as an in situ screening platform for inhibitors and essential enzyme mutations.Semantic proximity Read ↗

Non-mevalonate isoprenoid biosynthesis: enzymes, genes and inhibitorsSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.