Article
Molecular cloning and genetic analysis of an indole‐diterpene gene cluster from <i>Penicillium paxilli</i>
1 Feb 2001
Abstract excerpt
The indole-diterpene paxilline is a potent tremorgenic mammalian mycotoxin and a known inhibitor of maxi-K ion channels. The gene cluster responsible for paxilline biosynthesis in Penicillium paxilli was identified by mapping four large plasmid-induced chromosome deletions. The cluster is predicted to lie within a 50 kb region of chromosome Va and to contain 17 genes, including a geranylgeranyl pyrophosphate...
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