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Article

The sirodesmin biosynthetic gene cluster of the plant pathogenic fungus <i>Leptosphaeria maculans</i>

3 Aug 2004

Abstract excerpt

Sirodesmin PL is a phytotoxin produced by the fungus Leptosphaeria maculans, which causes blackleg disease of canola (Brassica napus). This phytotoxin belongs to the epipolythiodioxopiperazine (ETP) class of toxins produced by fungi including mammalian and plant pathogens. We report the cloning of a cluster of genes with predicted roles in the biosynthesis of sirodesmin PL and show via gene disruption that one of...

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PMID: 15387811
DOI: 10.1111/j.1365-2958.2004.04215.x

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