Article
Somatic beta-catenin mutation in gastric carcinoma--an infrequent event that is not specific for microsatellite instability.
Cancer letters - 10 Feb 2001
Tong J H, To K F, Ng E K, Lau J Y, Lee T L, Lo K W, Leung W K, Tang N L, Chan F K, Sung J J, Chung S C
Abstract excerpt
We screened 90 cases of gastric carcinoma (GCA) samples for beta-catenin exon 3 mutation and assessed its possible relationship with microsatellite instability (MSI). Three mutations were detected in two samples, including a single mutation in an intestinal type and double mutations in a diffuse type GCA. One of the mutations found in the diffuse type GCA sample was a non-sense mutation at codon 68 (CAG-->TAG)....
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