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Article

Sporadic fundic gland polyps: common gastric polyps arising through activating mutations in the beta-catenin gene.

The American journal of pathology - 1 Mar 2001

Abraham S C, Nobukawa B, Giardiello F M, Hamilton S R, Wu T T

Abstract excerpt

Fundic gland polyps (FGPs) are the most common gastric polyps. FGPs traditionally have been regarded as nondysplastic hamartomatous or hyperplastic lesions, but their pathogenesis remains unclear. We have recently shown that somatic adenomatous polyposis coli (APC) gene alterations are frequently present in FGPs associated with familial adenomatous polyposis (FAP), raising the possibility that mutations of the...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 11238048
DOI: 10.1016/s0002-9440(10)64047-3
PMCID: PMC1850357

Genes

FAP
APC

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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