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Article

Oxidation of human lens recombinant alphaA-crystallin and cysteine-deficient mutants.

Journal of molecular biology - 26 Jan 2001

Chen S J, Sun T X, Akhtar N J, Liang J J

Abstract excerpt

Disulfide cross-linking, one of the results of oxidative stress, has been thought to play an important role in cataractogenesis. High molecular mass (HMM) protein aggregation also contributes to cataract development, and a prevailing speculation is that disulfide cross-linking induces HMM aggregation. However, there is no direct evidence to support this speculation. Dimerization is an effect of disulfide...

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Share to Chromatography, Gel
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Share to Crystallins

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 11162107
DOI: 10.1006/jmbi.2000.4348

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Oxidation of human lens recombinant alphaA-crystallin and cysteine-deficient mutants.PMID 11162107Read ↗

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