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Article

The functionally important IL-10 promoter polymorphism (-1082G-->A) is not a major genetic regulator in recurrent spontaneous abortions.

Molecular human reproduction - 1 Feb 2001

Karhukorpi J, Laitinen T, Karttunen R, Tiilikainen A S

Abstract excerpt

Enhanced secretion of anti-inflammatory Th2 cytokines is a characteristic feature in normal physiological pregnancy. In recurrent spontaneous abortions (RSA), however, defective production of interleukin-10 (IL-10) and other Th2 cytokines has been shown in humans. Association studies have shown that a base exchange polymorphism (guanine-->adenine) at position -1082 of the IL-10 promoter is associated with...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 11160847
DOI: 10.1093/molehr/7.2.201

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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