Article
Cytokine gene polymorphisms and susceptibility to recurrent pregnancy loss in Iranian women.
Journal of reproductive immunology - 1 Apr 2005
Kamali-Sarvestani Eskandar, Zolghadri Jale, Gharesi-Fard Behrouz, Sarvari Jamal
Abstract excerpt
Recurrent pregnancy loss (RPL) is defined as three or more sequential abortions before the 20th week of gestation. There is increasing evidence to support an immunological mechanism for the occurrence of RPL. Defective production of T helper type 2 (Th2) and/or higher production of T helper type 1 (Th1) cytokines have been reported in RPL. As cytokine gene polymorphisms may be associated with different rates of...
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