Article
Lack of association between the TGF-beta1 gene polymorphisms and recurrent spontaneous abortion.
Journal of reproductive immunology - 1 Dec 2005
Amani Dawar, Dehaghani Alamtaj Samsami, Zolghadri Jaleh, Ravangard Fatemeh, Niikawa Norrio, Yoshiura Ko-ichiro, Ghaderi Abbas
Abstract excerpt
Transforming growth factor-beta1 (TGF-beta1) is produced by T regulatory lymphocytes (Treg), which play an important role in the physiology of pregnancy. Several polymorphisms of the TGF-beta1 gene (TGFB1) have been reported, some with an important correlation with TGF-beta1 production and disease severity. We performed an association study between TGFB1 polymorphisms and recurrent spontaneous abortion (RSA). We...
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