Article
Environmental stress and mutational load in diploid strains of the yeast Saccharomyces cerevisiae.
Proceedings of the National Academy of Sciences of the United States of America - 30 Jan 2001
Szafraniec K, Borts R H, Korona R
Abstract excerpt
The negative effect of permanent contamination of populations because of spontaneous mutations does not appear to be very high if judged from the relatively good health of humans or many wild and domesticated species. This is partly explained by the fact that, in diploids, the new mutations are usually located in heterozygous loci and therefore are masked by wild-type alleles. The expression of mutations at the...
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