Article
SLA2 mutations cause SWE1-mediated cell cycle phenotypes in Candida albicans and Saccharomyces cerevisiae.
Microbiology (Reading, England) - 1 Dec 2009
Gale Cheryl A, Leonard Michelle D, Finley Kenneth R, Christensen Leah, McClellan Mark, Abbey Darren, Kurischko Cornelia, Bensen Eric, Tzafrir Iris, Kauffman Sarah, Becker Jeff, Berman Judith
Abstract excerpt
The early endocytic patch protein Sla2 is important for morphogenesis and growth rates in Saccharomyces cerevisiae and Candida albicans, but the mechanism that connects these processes is not clear. Here we report that growth defects in cells lacking CaSLA2 or ScSLA2 are associated with a cell cycle delay that is influenced by Swe1, a morphogenesis checkpoint kinase. To establish how Swe1 monitors Sla2 function,...
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