Article
Possible human leukocyte antigen-mediated genetic interaction between type 1 and type 2 Diabetes.
The Journal of clinical endocrinology and metabolism - 1 Feb 2001
Li H, Lindholm E, Almgren P, Gustafsson A, Forsblom C, Groop L, Tuomi T
Abstract excerpt
We assessed the prevalence of families with both type 1 and type 2 diabetes in Finland; and we studied, in patients with type 2 diabetes, the association between a family history of type 1 diabetes, glutamic acid decarboxylase (GAD) antibodies (GADab), and type 1 diabetes-associated human leukocyte antigen (HLA) DQB1-genotypes. Further, in mixed type 1/type 2 diabetes families, we investigated whether sharing an...
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