Albomycin uptake via a ferric hydroxamate transport system of Streptococcus pneumoniae R6.

doi:10.1128/JB.00205-06

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Article

Albomycin uptake via a ferric hydroxamate transport system of Streptococcus pneumoniae R6.

Journal of bacteriology - 1 Jun 2006

Pramanik Avijit, Braun Volkmar

Abstract excerpt

The antibiotic albomycin is highly effective against Streptococcus pneumoniae, with an MIC of 10 ng/ml. The reason for the high efficacy was studied by measuring the uptake of albomycin into S. pneumoniae. Albomycin was transported via the system that transports the ferric hydroxamates ferrichrome and ferrioxamine B. These two ferric hydroxamates antagonized the growth inhibition by albomycin and salmycin....

Topics

Base Sequence
Biological Transport
DNA Primers
Ferric Compounds
Ferrichrome
Genome, Bacterial
Genotype
Hydroxamic Acids
Iron
Kinetics
Restriction Mapping
Streptococcus pneumoniae
Streptonigrin

Source

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Identifiers

PMID: 16707680
DOI: 10.1128/JB.00205-06
PMCID: PMC1482914

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