Article
Familial segregation of venous thromboembolism.
Journal of thrombosis and haemostasis : JTH - 1 May 2004
Heit J A, Phelps M A, Ward S A, Slusser J P, Petterson T M, De Andrade M
Abstract excerpt
BACKGROUND: Venous thromboembolism (VTE) is postulated as a complex disease, but the heritability and mode of inheritance are uncertain. OBJECTIVE: To determine if VTE (i) segregates in families; (ii) is attributable to inheritance, shared environment, or both; and (iii) the possible mode of inheritance. PATIENTS AND METHODS: In a family-based study of relatives from 751 probands (60% female) with objectively...
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