Article
Incidence of venous thromboembolism in families with inherited thrombophilia.
Thrombosis and haemostasis - 1 Feb 1999
Simioni P, Sanson B J, Prandoni P, Tormene D, Friederich P W, Girolami B, Gavasso S, Huisman M V, Büller H R, Wouter ten Cate J, Girolami A, Prins M H
Abstract excerpt
The risk of spontaneous or risk-period related venous thromboembolism in family members of symptomatic carriers of antithrombin (AT), protein C (PC) or protein S (PS) defects, as well as of the Factor V Leiden mutation is still undefined. We performed a retrospective cohort study in family members (n = 793) of unselected patients with a documented venous thromboembolism and one of these deficiencies to make an...
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