Article
Response and determinants of sensitivity to paclitaxel in human non-small cell lung cancer tumors heterotransplanted in nude mice.
Clinical cancer research : an official journal of the American Association for Cancer Research - 1 Dec 2000
Perez-Soler R, Kemp B, Wu Q P, Mao L, Gomez J, Zeleniuch-Jacquotte A, Yee H, Lee J S, Jagirdar J, Ling Y H
Abstract excerpt
The lack of tumor models that can reliably predict for response to anticancer agents remains a major deficiency in the field of experimental cancer therapy. Although heterotransplants of certain human solid tumors can be successfully grown in nude mice, they have never been appropriately explored for prediction of in vivo chemosensitivity to anticancer agents. We determined the tumor response rate and studied the...
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