Article
p53-independent response of a human breast carcinoma xenograft to radioimmunotherapy.
Cancer - 15 Dec 1997
Winthrop M D, DeNardo S J, Muenzer J T, Chi S G, Gumerlock P H
Abstract excerpt
BACKGROUND: Radiation-induced DNA damage resulting in p53 protein attachment and downstream gene activation has been considered a major mechanism for tumor response to low dose rate radiation therapy. In this study, the mechanism of tumor response, and p53 gene status as well as levels of expression of p53 pathway genes were investigated in a human breast tumor (HBT 3477) before and after...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
