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Article

The growth and metastasis of human, HER-2/neu-overexpressing tumor cell lines in male SCID mice.

Breast cancer research and treatment - 1 Jun 2000

Clinchy B, Gazdar A, Rabinovsky R, Yefenof E, Gordon B, Vitetta E S

Abstract excerpt

HER-2/neu is overexpressed on a variety of human adenocarcinomas and overexpression has been associated with a poor prognosis. For this reason, HER-2 has become an attractive target for immunotherapy. To facilitate testing of anti-HER-2-monoclonal antibodies (MAbs) and immunotoxins (ITs), we have evaluated the in vivo growth and metastatic spread of three HER-2-overexpressing human breast cancer cell lines...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 10965998
DOI: 10.1023/a:1006494001861

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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