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Article

Differential regulation of germ line apoptosis and germ cell differentiation by CPEB family members in C. elegans.

PloS one - 1 Jan 2017

Singh Kapil Dev, Zheng Xue, Milstein Stuart, Keller Martin, Roschitzki Bernd, Grossmann Jonas, Hengartner Michael O

Abstract excerpt

Cytoplasmic polyadenylation element binding (CPEB) proteins are evolutionary conserved RNA-binding proteins that control mRNA polyadenylation and translation. Orthologs in humans and other vertebrates are mainly involved in oogenesis. This is also the case for the C. elegans CPEB family member CPB-3, whereas two further CPEB proteins (CPB-1 and FOG-1) are involved in spermatogenesis. Here we describe the...

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Identifiers

PMID: 28759574
DOI: 10.1371/journal.pone.0182270
PMCID: PMC5536308

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