Article
Biology and Treatment of Paget's Disease of Bone.
Journal of cellular biochemistry - 1 Feb 2016
Vallet Mahéva, Ralston Stuart H
Abstract excerpt
Paget's disease of bone (PDB) is a common skeletal disorder characterized by increased and disorganized bone remodeling affecting one or more skeletal sites. Although some patients are asymptomatic others develop complications such as bone pain, deformity, nerve compression syndromes, and fragility fractures. Genetic factors play an important role in the pathogenesis of PDB and there is strong evidence that...
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