Article
Association of the apolipoprotein E gene with age-related macular degeneration: possible effect modification by family history, age, and gender.
Molecular vision - 31 Dec 2000
Schmidt S, Saunders A M, De La Paz MA, Postel E A, Heinis R M, Agarwal A, Scott W K, Gilbert J R, McDowell J G, Bazyk A, Gass J D, Haines J L, Pericak-Vance M A
Abstract excerpt
PURPOSE: Age-related macular degeneration (AMD) is a complex disorder affecting older adults in which genetic factors are likely to play a role. It has been previously suggested that the e4 allele of the apolipoprotein E (APOE) gene may have a protective effect on AMD risk and that the e2 allele may increase disease risk. The purpose of our study was to examine whether an independent data set would support the...
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