Article

Hypercytokinemia in familial hemophagocytic lymphohistiocytosis

1991-12-01

Abstract excerpt

Familial hemophagocytic lymphohistiocytosis (FHL) is a frequently missed and almost uniformly fatal childhood disorder. It is characterized by fever, hepatosplenomegaly, cytopenia, coagulopathy, and hypertriglyceridemia. The pathogenesis of FHL is not known but the above clinical and laboratory findings are compatible with reported in vitro and in vivo effects of several inflammatory cytokines. We measured circula...

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Literature Corpus work: b9e09b41-c33b-5567-a957-399cb53b6af4
DOI: 10.1182/blood.v78.11.2918.bloodjournal78112918

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