Article
Hepatitis C virus and interferon resistance.
Microbes and infection - 1 Nov 2000
Taylor D R, Shi S T, Lai M M
Abstract excerpt
Interferon plays a critical role in the host's natural defense against viral infections and in their treatment. It is the only therapy for hepatitis C virus (HCV) infection; however, many virus isolates are resistant. Several HCV proteins have been shown to possess properties that enable the virus to evade the interferon-mediated cellular antiviral responses.
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