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Article

p53 binding protein 1 (53BP1) is an early participant in the cellular response to DNA double-strand breaks.

The Journal of cell biology - 25 Dec 2000

Schultz L B, Chehab N H, Malikzay A, Halazonetis T D

Abstract excerpt

p53 binding protein 1 (53BP1), a protein proposed to function as a transcriptional coactivator of the p53 tumor suppressor, has BRCT domains with high homology to the Saccharomyces cerevisiae Rad9p DNA damage checkpoint protein. To examine whether 53BP1 has a role in the cellular response to DNA damage, we probed its intracellular localization by immunofluorescence. In untreated primary cells and U2OS...

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Identifiers

PMID: 11134068
DOI: 10.1083/jcb.151.7.1381
PMCID: PMC2150674

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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p53 binding protein 1 (53BP1) is an early participant in the cellular response to DNA double-strand breaks.PMID 11134068Read ↗

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