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Article

53BP1 exchanges slowly at the sites of DNA damage and appears to require RNA for its association with chromatin.

Journal of cell science - 1 May 2005

Pryde Fiona, Khalili Shirin, Robertson Kathryn, Selfridge Jim, Ritchie Ann-Marie, Melton David W, Jullien Denis, Adachi Yasuhisa

Abstract excerpt

53BP1 protein is re-localized to the sites of DNA damage after ionizing radiation (IR) and is involved in DNA-damage-checkpoint signal transduction. We examined the dynamics of GFP-53BP1 in living cells. The protein starts to accumulate at the sites of DNA damage 2-3 minutes after damage inductio...

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Source

Identifiers

PMID: 15840649
DOI: 10.1242/jcs.02336

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026. Prepared record publication-15840649-2026-09-01.1. Manifest publication-graph-cohort-2026-09-01.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 1 Sept 2026.

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53BP1 exchanges slowly at the sites of DNA damage and appears to require RNA for its association with chromatin.PMID 15840649Read ↗

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