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Article

Cellular responses to DNA double-strand breaks after low-dose γ-irradiation

28 Apr 2009

Abstract excerpt

DNA double-strand breaks (DSBs) are a serious threat to genome stability and cell viability. Although biological effects of low levels of radiation are not clear, the risks of low-dose radiation are of societal importance. Here, we directly monitored induction and repair of single DSBs and quantitatively analyzed the dynamics of interaction of DNA repair proteins at individual DSB sites in living cells using...

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PMID: 19401436
DOI: 10.1093/nar/gkp237

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