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Article

Experimental evolution recapitulates natural evolution.

Philosophical transactions of the Royal Society of London. Series B, Biological sciences - 29 Nov 2000

Wichman H A, Scott L A, Yarber C D, Bull J J

Abstract excerpt

Genomes of the closely related bacteriophages phiX174 and S13 are 5386 bases long and differ at 114 nucleotides, affecting 28 amino acids. Both parental phages were adapted to laboratory culture conditions in replicate lineages and analysed for nucleotide changes that accumulated experimentally Of the 126 experimental substitutions, 90% encoded amino-acid changes, and 62% of the substitutions occurred in parallel...

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Identifiers

PMID: 11127915
DOI: 10.1098/rstb.2000.0731
PMCID: PMC1692893

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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