Genomewide patterns of substitution in adaptively evolving populations of the RNA bacteriophage MS2.

Abstract excerpt

Experimental evolution of bacteriophage provides a powerful means of studying the genetics of adaptation, as every substitution contributing to adaptation can be identified and characterized. Here, I use experimental evolution of MS2, an RNA bacteriophage, to study its adaptive response to a novel environment. To this end, three lines of MS2 were adapted to rapid growth and lysis at cold temperature for a minimum...

Topics

• Adaptation, Physiological
• Amino Acid Substitution
• Base Sequence
• Chromosome Mapping
• Evolution, Molecular
• Gene Frequency
• Genome, Viral
• Levivirus
• Molecular Sequence Data
• Nucleic Acid Conformation
• Phenotype