Article
Graft-versus-leukemia reactions in allogeneic chimeras
9 Sept 2003
Abstract excerpt
There is a strong graft-versus-leukemia (GVL) effect of allogeneic stem cell transplantation (SCT) due to elimination of tumor cells by alloimmune effector lymphocytes. When leukemia relapses after allogeneic SCT, donor lymphocyte transfusions (DLTs) can induce sustained remissions in some patients. This review summarizes the current status on clinical use of DLT, the basis of GVL reactions, problems associated...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
