Mutations affecting the expression of the MOX gene encoding peroxisomal methanol oxidase in Hansenula polymorpha.

doi:10.1007/s002940000142

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Article

Mutations affecting the expression of the MOX gene encoding peroxisomal methanol oxidase in Hansenula polymorpha.

Current genetics - 1 Nov 2000

Vallini V, Berardi E, Strabbioli R

Abstract excerpt

In this study, aimed at identifying genetic factors acting positively upon the MOX gene, we report the isolation and characterisation of several methanol utilisation-defective (Mut-) mutants of Hansenula polymorpha. These fall into 12 complementation groups, eight of which show significant reductions in alcohol (methanol) oxidase activity in methanol. Three of these groups, identifying the MUT3, MUT5 and MUT10...

Topics

Alcohol Oxidoreductases
Genes, Fungal
Genes, Reporter
Microscopy, Electron
Mutation
Peroxisomes
Pichia
RNA, Messenger

Source

Open in PubMed

Identifiers

PMID: 11126774
DOI: 10.1007/s002940000142

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