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Article

Characterization of peroxisome-deficient mutants of Hansenula polymorpha.

Current genetics - 1 Aug 1995

Tan X, Titorenko V I, van der Klei I J, Sulter G J, Haima P, Waterham H R, Eyers M, Harder W, Veenhuis M, Cregg J M

Abstract excerpt

In the methylotrophic yeast Hansenula polymorpha, approximately 25% of all methanol-utilization-defective (Mut-) mutants are affected in genes required for peroxisome biogenesis (PER genes). Previously, we reported that one group of per mutants, termed Pim-, are characterized by the presence of a few small peroxisomes with the bulk of peroxisomal enzymes located in the cytosol. Here, we describe a second major...

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PMID: 8529271
DOI: 10.1007/BF00309784

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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Characterization of peroxisome-deficient mutants of Hansenula polymorpha.PMID 8529271Read ↗

Hansenula polymorpha: an attractive model organism for molecular studies of peroxisome biogenesis and function.Semantic proximity Read ↗

Peroxisome biogenesis in Hansenula polymorpha: different mutations in genes, essential for peroxisome biogenesis, cause different peroxisomal mutant phenotypes.Semantic proximity Read ↗

Peroxisome biogenesis in the yeast Hansenula polymorpha is controlled by a complex set of interacting gene products.Semantic proximity Read ↗

Peroxisomes in the methylotrophic yeast Hansenula polymorpha do not necessarily derive from pre-existing organelles.Semantic proximity Read ↗

Restoration of peroxisome formation in two conditional peroxisome-deficient mutants of Hansenula polymorpha during growth of cells on specific organic nitrogen sources.Semantic proximity Read ↗

Isolation of mutants of Hansenula polymorpha defective in the assembly of octameric alcohol oxidase.Semantic proximity Read ↗

Selective inactivation of alcohol oxidase in two peroxisome-deficient mutants of the yeast Hansenula polymorpha.Semantic proximity Read ↗

Synthesis and subcellular location of peroxisomal membrane proteins in a peroxisome-deficient mutant of the yeast Hansenula polymorpha.Semantic proximity Read ↗

The Hansenula polymorpha per6 mutant is affected in two adjacent genes which encode dihydroxyacetone kinase and a novel protein, Pak1p, involved in peroxisome integrity.Semantic proximity Read ↗

Methanol metabolism in a peroxisome-deficient mutant of Hansenula polymorpha: a physiological study.Semantic proximity Read ↗

Mutations affecting the expression of the MOX gene encoding peroxisomal methanol oxidase in Hansenula polymorpha.Semantic proximity Read ↗

The Hansenula polymorpha PER1 gene is essential for peroxisome biogenesis and encodes a peroxisomal matrix protein with both carboxy- and amino-terminal targeting signals.Semantic proximity Read ↗

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