Article
The Hansenula polymorpha MOX gene presents two alternative transcription start points differentially utilized and sensitive to respiratory activity.
European journal of biochemistry - 1 Jun 2003
Genu Victor, Gödecke Stefanie, Hollenberg Cornelis P, Pereira Gonçalo G
Abstract excerpt
The peroxisomal methanol metabolism of Hansenula polymorpha depends on a group of genes that are coordinately regulated. Methanol oxidase (Mox) plays a key role in this pathway and its synthesis has been shown to be regulated at the transcriptional level. MOX expression is strongly repressed on glucose and activated on glycerol or methanol. In this study we have identified two MOX transcripts that are...
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