Article
Cytopathogenic and Noncytopathogenic RNA Replicons of Classical Swine Fever Virus
1 Sept 1999
Abstract excerpt
To determine the minimal requirements for autonomous RNA replication of classical swine fever virus (CSFV), genomes having in-frame deletions within the genes for structural and flanking nonstructural proteins were constructed, based on an infectious cDNA clone of CSFV Alfort/187. RNA was transcribed in vitro from the respective plasmids and transfected into SK-6 swine kidney cells. The replication competence of...
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