Article
Identification of functional regions within invasion plasmid antigen C (IpaC) of Shigella flexneri.
Molecular microbiology - 1 Jan 2001
Picking W L, Coye L, Osiecki J C, Barnoski Serfis A, Schaper E, Picking W D
Abstract excerpt
Shigella flexneri causes bacillary dysentery with symptoms resulting from the inflammation that accompanies bacterial entry into the cells of the colonic epithelium. The effectors of S. flexneri invasion are the Ipa proteins, particularly IpaB and IpaC, which are secreted at the host-pathogen interface following bacterial contact with a host cell. Of the purified Ipa proteins, only IpaC has been shown to possess...
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