Article
Diversity of T-cell receptor gene rearrangements in South Indian patients with common acute lymphoblastic leukemia.
Iranian journal of immunology : IJI - 1 Sept 2009
Sudhakar Natarajan, Nancy Nirmala Karunakaran, Rajalekshmy Kamalalayam Raghavan, Rajkumar Thangarajan
Abstract excerpt
BACKGROUND: Precursor B-Acute Lymphoblastic Leukemia (precursor B-ALL) occurs due to the uncontrolled proliferation of B-lymphoid precursors arrested at a particular stage of B-cell development. Precursor-B-ALL is classified mainly into pro-B-ALL, common-ALL and pre-B-ALL. The Common Acute Lymphoblastic Antigen CD10 is the marker for common-ALL. OBJECTIVE: This study was aimed to examine the diversity of T-cell...
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