Article
Diversity of T-cell receptor gene rearrangements in South Indian patients with common acute lymphoblastic leukemia.
Iranian journal of immunology : IJI - 1 Sept 2009
Sudhakar Natarajan, Nancy Nirmala Karunakaran, Rajalekshmy Kamalalayam Raghavan, Rajkumar Thangarajan
Abstract excerpt
BACKGROUND: Precursor B-Acute Lymphoblastic Leukemia (precursor B-ALL) occurs due to the uncontrolled proliferation of B-lymphoid precursors arrested at a particular stage of B-cell development. Precursor-B-ALL is classified mainly into pro-B-ALL, common-ALL and pre-B-ALL. The Common Acute Lymphoblastic Antigen CD10 is the marker for common-ALL. OBJECTIVE: This study was aimed to examine the diversity of T-cell...
Topics
- Adolescent
- Child
- Child, Preschool
- Female
- Gene Rearrangement, delta-Chain T-Cell Antigen Receptor
- Gene Rearrangement, gamma-Chain T-Cell Antigen Receptor
- Genetic Variation
- Humans
- India
- Male
