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Article

A Human Breast Epithelial Cell Type with Stem Cell Characteristics as Target Cells for Carcinogenesis

1 Jan 2001

Abstract excerpt

Two types of human breast epithelial cells (HBEC) have been characterized. In contrast to Type II HBEC, which express basal epithelial cell phenotypes, Type I HBEC are deficient in gap junctional intercellular communication and are capable of anchorage-independent growth and of expressing luminal epithelial cell markers, estrogen receptors, and stem cell characteristics (i.e. the ability to differentiate into...

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PMID: 11121235
DOI: 10.1667/0033-7587(2001)155[0201:ahbect]2.0.co;2

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