Age and the means of bypassing stasis influence the intrinsic subtype of immortalized human mammary epithelial cells

Abstract excerpt

Based on molecular features, breast cancers are grouped into intrinsic subtypes that have different prognoses and therapeutic response profiles. With increasing age, breast cancer incidence increases, with hormone receptor-positive and other luminal-like subtype tumors comprising a majority of cases. It is not known at what stage of tumor progression subtype specification occurs, nor how the process of aging...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Breast Cancer Treatment Studies
• Share to Cancer Cells and Metastasis
• Share to Cancer-related Molecular Pathways