Article
Search for bipolar disorder susceptibility loci: the application of a modified genome scan concentrating on gene-rich regions.
American journal of medical genetics - 4 Dec 2000
Murphy V E, Mynett-Johnson L A, Claffey E, Bergin P, McAuliffe M, Kealey C, McKeon P
Abstract excerpt
Conducting genome wide screens for evidence of genetic linkage has become a well-established method for identifying regions of the human genome harboring susceptibility loci for complex disorders. For bipolar disorder, a number of such studies have been performed, and several regions of the genome have potentially been implicated in the disorder. The classic design for a genome screen involves examining...
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