Article
Role of NF-κB and Myc Proteins in Apoptosis Induced by Hepatitis B Virus HBx Protein
1 Jan 2001
Abstract excerpt
Chronic infection with hepatitis B virus (HBV) promotes a high level of liver disease and cancer in humans. The HBV HBx gene encodes a small regulatory protein that is essential for viral replication and is suspected to play a role in viral pathogenesis. HBx stimulates cytoplasmic signal transduction pathways, moderately stimulates a number of transcription factors, including several nuclear factors, and in...
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