Article
BRAF alterations are frequent in cerebellar low-grade astrocytomas with diffuse growth pattern.
Journal of neuropathology and experimental neurology - 1 Jul 2012
Ida Cristiane M, Lambert Sally R, Rodriguez Fausto J, Voss Jesse S, Mc Cann Brooke E, Seys Amber R, Halling Kevin C, Collins V Peter, Giannini Caterina
Abstract excerpt
Cerebellar low-grade astrocytomas with a diffuse pattern of growth are uncommon, comprising World Health Organization (WHO) grade II diffuse astrocytomas (DA) and a minority of WHO grade I pilocytic astrocytomas (PA), so-called PA, "diffuse variant." Among 106 cerebellar low-grade astrocytomas (WHO grade I and II) operated on at the Mayo Clinic (1984-2010), we identified 19 such cases: 8 PA, "diffuse variant," 5...
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