Control of endoreduplication domains in the Drosophila gut by the knirps and knirps-related genes.

doi:10.1016/s0925-4773(00)00512-8

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Article

Control of endoreduplication domains in the Drosophila gut by the knirps and knirps-related genes.

Mechanisms of development - 1 Jan 2001

Fuss B, Meissner T, Bauer R, Lehmann C, Eckardt F, Hoch M

Abstract excerpt

Endoreduplication cycles that lead to an increase of DNA ploidy and cell size occur in distinct spatial and temporal patterns during Drosophila development. Only little is known about the regulation of these modified cell cycles. We have investigated fore- and hindgut development and we present evidence that the Drosophila knirps and knirps-related genes are key components to spatially restrict endoreduplication...

Topics

Animals
Bromodeoxyuridine
Cell Cycle
DNA
DNA-Binding Proteins
Digestive System
Down-Regulation
Drosophila
Drosophila Proteins
Epithelium
Immunohistochemistry

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

In Situ Hybridization

Models, Biological

Mutation

Ploidies

Repressor Proteins

Signal Transduction

Time Factors

Source

Open in PubMed

Identifiers

PMID: 11118880
DOI: 10.1016/s0925-4773(00)00512-8

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