Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

A genome-scale in vivo RNAi analysis of epithelial development in Drosophila identifies new proliferation domains outside of the stem cell niche.

Journal of cell science - 15 Jun 2014

Berns Nicola, Woichansky Innokenty, Friedrichsen Steffen, Kraft Nadine, Riechmann Veit

Abstract excerpt

The Drosophila oogenesis system provides an excellent model to study the development of epithelial tissues. Here, we report the first genome-scale in vivo RNA interference (RNAi) screen for genes controlling epithelial development. By directly analysing cell and tissue architecture we identified 1125 genes, which we assigned to seven different functions in epithelial formation and homeostasis. We validated the...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Endosomal Sorting Complexes Required for Transport
Share to Epithelium

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Genome, Insect

Share to Oogenesis

Share to Ovarian Follicle

Share to Receptors, Notch

Share to Stem Cell Niche

Share to Ubiquitin

Source

Identifiers

PMID: 24762813
DOI: 10.1242/jcs.144519

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

A genome-scale in vivo RNAi analysis of epithelial development in Drosophila identifies new proliferation domains outside of the stem cell niche.PMID 24762813Read ↗

A single cell atlas reveals unanticipated cell type complexity in <i>Drosophila</i> ovariesSemantic proximity Read ↗

Regulation of Epithelial Stem Cell Replacement and Follicle Formation in the Drosophila OvarySemantic proximity Read ↗

Whole-animal genome-wide RNAi screen identifies networks regulating male germline stem cells in Drosophila.Semantic proximity Read ↗

Daughterless coordinates somatic cell proliferation, differentiation and germline cyst survival during follicle formation in Drosophila.Semantic proximity Read ↗

A Targeted RNAi Screen Reveals Drosophila Female-Sterile Genes That Control the Size of Germline Stem Cell Niche During Development.Semantic proximity Read ↗

Opposing JAK-STAT and Wnt signaling gradients define a stem cell domain by regulating differentiation at two borders.Semantic proximity Read ↗

The Drosophila tumor suppressor vps25 prevents nonautonomous overproliferation by regulating notch trafficking.Semantic proximity Read ↗

Genome-wide RNAi screen identifies networks involved in intestinal stem cell regulation in Drosophila.Semantic proximity Read ↗

RNAi-Based Techniques for the Analysis of Gene Function in Drosophila Germline Stem Cells.Semantic proximity Read ↗

Early female germline development in <i>Xenopus laevis</i> : stem cells, nurse cells and germline cystsSemantic proximity Read ↗

The <i>Drosophila</i> histone methyl-transferase SET1 coordinates multiple signaling pathways in regulating male germline stem cell maintenance and differentiationSemantic proximity Read ↗

A Genetic Mosaic Screen Reveals Ecdysone-Responsive Genes Regulating Drosophila Oogenesis.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.