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Article

Frequent alterations of LOH11CR2A, PIG8 and CHEK1 genes at chromosomal 11q24.1-24.2 region in breast carcinoma: clinical and prognostic implications.

Molecular oncology - 1 Oct 2011

Sinha Satyabrata, Singh Ratnesh K, Bhattacharya Nilanjana, Mukherjee Nupur, Ghosh Susmita, Alam Neyaz, Roy Anup, Roychoudhury Susanta, Panda Chinmay Kumar

Abstract excerpt

To understand the importance of frequent deletions at chromosome 11q24.1-24.2 region in breast carcinoma, alterations (deletion/methylation) of the candidate genes LOH11CR2A, ROBO3, ROBO4, HEPACAM, PIG8 and CHEK1 located in this region were analyzed in 106 breast carcinoma samples. Among these genes, LOH11CR2A showed highest frequency of deletion (56%), followed by PIG8 (35%), CHEK1 (31%) and ROBO3/ROBO4/HEPACAM...

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Source

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Identifiers

PMID: 21803008
DOI: 10.1016/j.molonc.2011.06.005
PMCID: PMC5528301

Genes

CHEK1
HEPACAM
ROBO3
ROBO4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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